But what would considered a significant percentage rise in its cituation and the price of the stock

A significant percentage rise in the stock price of Booking Holdings (BKNG) would depend on various factors such as the company's financial performance, market conditions, and industry trends. Historically, BKNG has shown strong performance with significant growth in earnings and revenues.

To determine a significant percentage rise, we can look at the stock's performance over the past year as a benchmark. Here are some key points to consider:

1. **Recent Performance**: BKNG has experienced a 60.8% gain in the past year, outperforming the industry's growth of 47.6%. This indicates a strong overall trend.
2. **Analyst Ratings and Price Targets**: Analysts have set a consensus recommendation of "Moderate Buy" with an average twelve-month target price of $4,068.32, suggesting potential for further growth. Additionally, Goldman Sachs maintains a Neutral rating with a price target of $3,870.00, indicating confidence in the stock's performance.
3. **Historical Returns**: BKNG has an impressive historical annualized return of 23.15% over the past 15 years, which provides a reference for the stock's potential for significant growth.

Based on these factors, a significant percentage rise in the stock price of BKNG could be considered to be:

1. **Above the Industry Average**: A rise that outperforms the industry average growth rate would be considered significant.
2. **Above Analyst Price Targets**: A stock price increase that surpasses the average analyst price target would also be considered significant.
3. **Historical Returns**: A rise that is in line with or exceeds the stock's historical annualized return would also be considered significant.

Given these criteria, a 25% rise in the stock price of BKNG would be considered significant, as it aligns with the stock's historical performance and the current analyst expectations.