Will AGIO's Q1 2025 forecast beat market expectations?

**AGIO's Q1 2025 forecast suggests a challenging quarter ahead**, and it is unlikely to meet market expectations as indicated by the following points:

1. **Expected Negative EPS**: The estimated EPS for AGIO in Q1 2025 is -$1.8, which suggests a significant loss for the period. This is a stark contrast to the positive earnings trend observed in the previous quarter (Q4 2024), where net Pyrukynd revenue saw a 51% increase.

2. **Revenue Projection Below Previous Quarter's Level**: The estimated revenue for Q1 2025 is $10.37 million. This is notably lower than the net Pyrukynd revenue of $10.7 million reported for Q4 2024. The decline in revenue projection indicates a potential slowdown in business activity or market demand for AGIO's products.
3. **Market Expectations**: The average analyst price target for AGIO over the past three months is $62.00, which is significantly higher than the estimated EPS of -$1.8. This disparity suggests that the market may be anticipating a stronger financial performance from AGIO in Q1 2025.
4. **Recent Performance and Pipeline Developments**: While AGIO has made notable progress in its pipeline and has seen significant revenue growth in recent quarters, the upcoming quarter's forecast does not reflect this positive momentum. The company's strong financial position and strategic pipeline advancements have not translated into a positive EPS forecast for Q1 2025.

In conclusion, AGIO's Q1 2025 forecast indicates a difficult period ahead, with a projected negative EPS and lower revenue compared to the previous quarter. Given the market's expectations and the company's recent performance, it is unlikely that AGIO's Q1 2025 forecast will meet market expectations.